List of publications

Updike’s lab, Nature Communications : RG/RGG repeats in the C. elegans homologs of Nucleolin and GAR1 contribute to sub-nucleolar phase separation
Pituello’s lab, Development : Single-cell imaging of cell cycle reveals that tissue-scale g1 lengthening involves cdc25b induced cell-to-cell heterogeneity in neural progenitor cells
Rollin’s lab, Cell Reports Methods : Quantification of tissue-specific protein translation in whole C. elegans using O-propargyl-puromycin labeling and fluorescence microscopy
Godwin’s lab, stem-cell-reports : Tissue origin of cytotoxic natural killer cells dictates their differential roles in mouse digit tip regeneration and progenitor cell survival.
Jun-Yeong Lee, Ian Davis, Elliot H. H. Youth, Jonghwan Kim, Gary Churchill, James Godwin, Ron Korstanje, and Samuel Beck. Science Advances (2021) DOI: 10.1126/sciadv.abj9111.
Vicki P. Losick and Levi G. Duhaime. Cell Reports (2021) DOI: 10.1016/j.celrep.2021.109827
Ryan J Debuque , Andrew J Hart, Gabriela H Johnson, Nadia A Rosenthal, James W Godwin. Front. Cell Dev. Biol (2021) (DOI: 10.3389/fcell.2021.750587).
Tilley L, Papadopoulos S-C, Pende M, Fei J-F, Murawala.The use of transgenics in the laboratory axolotl. Developmental Dynamics (2021) (doi/10.1002/dvdy.213).
Rose Besen-McNally,Kayla J. Gjelsvik, Vicki P. Losick. Wound-induced polyploidization is dependent on Integrin-Yki signaling. Biology open (2021)doi: 10.1242/bio.055996.
Breton, T.S., Sampson, W.G.B., Clifford, B. et al. Characterization of the G protein-coupled receptor family SREB across fish evolution. Sci Rep 11, 12066 (2021).
Bailey EC, Dehn AS, Gjelsvik KJ, Besen-McNally R, Losick VP. A Drosophila Model to Study Wound-induced Polyploidization. J Vis Exp [Internet]. 2020 Jun 9;(160).
Cirrincione AM, Pellegrini AD, Dominy JR, Benjamin ME, Utkina-Sosunova I, Lotti F, Jergova S, Sagen J, Rieger S. Paclitaxel-induced peripheral neuropathy is caused by epidermal ROS and mitochondrial damage through conserved MMP-13 activation. Sci Rep [Internet]. 2020 Mar 4;10(1):3970.
FitzSimons M, Beauchemin M, Smith AM, Stroh EG, Kelpsch DJ, Lamb MC, Tootle TL, Yin VP.”> Cardiac injury modulates critical components of prostaglandin E2 signaling during zebrafish heart regeneration. Sci Rep [Internet]. 2020 Feb 20;10(1):3095.
Gans I, Hartig EI, Zhu S, Tilden AR, Hutchins LN, Maki NJ, Graber JH, Coffman JA. Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity. Sci Rep [Internet]. 2020 Jul 10;10(1):11415.
Kinne R, Spokes KC, Silva P. Sugar uptake, metabolism, and chloride secretion in the rectal gland of the spiny dogfish Squalus acanthias. Am J Physiol Regul Integr Comp Physiol [Internet]. 2020 Jul 1;319(1):R96–R105.
Reed KJ, Svendsen JM, Brown KC, Montgomery BE, Marks TN, Vijayasarathy T, Parker DM, Nishimura EO, Updike DL, Montgomery TA. Widespread roles for piRNAs and WAGO-class siRNAs in shaping the germline transcriptome of Caenorhabditis elegans. Nucleic Acids Res [Internet]. 2020;48(4):1811–1827.
Adamla F, Rollins J, Newsom M, Snow S, Schosserer M, Heissenberger C, Horrocks J, Rogers AN, Ignatova Z. A Novel Caenorhabditis Elegans Proteinopathy Model Shows Changes in mRNA Translational Frameshifting During Aging. Cell Physiol Biochem [Internet]. 2019;52(5):970–983.
Grendler J, Lowgren S, Mills M, Losick VP. Wound-induced polyploidization is driven by Myc and supports tissue repair in the presence of DNA damage. Development [Internet]. 2019;146(15).
Lan J, Rollins JA, Zang X, Wu D, Zou L, Wang Z, Ye C, Wu Z, Kapahi P, Rogers AN, Chen D. Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity. Cell Rep [Internet]. 2019;28(4):1050-1062.e6.
Mahringer A, Bernd A, Miller DS, Fricker G. Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules. Biol Chem [Internet]. 2019;400(10):1335–1345.
Marnik EA, Fuqua JH, Sharp CS, Rochester JD, Xu EL, Holbrook SE, Updike DL. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Genetics [Internet]. 2019;213(3):923–939.
Müller-Deile J, Schenk H, Schroder P, Schulze K, Bolaños-Palmieri P, Siegerist F, Endlich N, Haller H, Schiffer M. Circulating factors cause proteinuria in parabiotic zebrafish. Kidney Int [Internet]. 2019;96(2):342–349.
Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M. Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy. Biol Open [Internet]. 2019 Mar 4;8(3).
Schenk H, Müller-Deile J, Schroder P, Bolaños-Palmieri P, Beverly-Staggs L, White R, Bräsen JH, Haller H, Schiffer M. Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model. Sci Rep [Internet]. 2019;9(1):17718.
Schenk H, Masseli A, Schroder P, Bolaños-Palmieri P, Beese M, Hegermann J, Bräsen JH, Haller H. Sulfatases, in Particular Sulf1, Are Important for the Integrity of the Glomerular Filtration Barrier in Zebrafish. Biomed Res Int [Internet]. 2019;2019:4508048.
Smith AM, Dykeman CA, King BL, Yin VP. Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration. iScience [Internet]. 2019 May 31;15:1–15.
Tossidou I, Teng B, Worthmann K, Müller-Deile J, Jobst-Schwan T, Kardinal C, Schroder P, Bolanos-Palmieri P, Haller H, Willerding J, Drost DM, de Jonge L, Reubold T, Eschenburg S, Johnson RI, Schiffer M. Tyrosine Phosphorylation of CD2AP Affects Stability of the Slit Diaphragm Complex. J Am Soc Nephrol [Internet]. 2019;30(7):1220–1237.
Beck S, Rhee C, Song J, Lee B-K, LeBlanc L, Cannon L, Kim J.”> Implications of CpG islands on chromosomal architectures and modes of global gene regulation. Nucleic Acids Res [Internet]. 2018;46(9):4382–4391.
Hersh TA, Dimond AL, Ruth BA, Lupica N V, Bruce JC, Kelley JM, King BL, Lutton B V. A role for the CXCR4-CXCL12 axis in the little skate, Leucoraja erinacea. Am J Physiol Regul Integr Comp Physiol [Internet]. 2018;315(2):R218–R229.
Müller-Deile J, Schröder P, Beverly-Staggs L, Hiss R, Fiedler J, Nyström J, Thum T, Haller H, Schiffer M. Overexpression of preeclampsia induced microRNA-26a-5p leads to proteinuria in zebrafish. Sci Rep [Internet]. 2018;8(1):3621.
Neuman RI, van Kalmthout JAM, Pfau DJ, Menendez DM, Young LH, Forrest JN. AMP-activated protein kinase and adenosine are both metabolic modulators that regulate chloride secretion in the shark rectal gland ( Squalus acanthias). Am J Physiol Cell Physiol [Internet]. 2018;314(4):C473–C482.
Rinschen MM, Gödel M, Grahammer F, Zschiedrich S, Helmstädter M, Kretz O, Zarei M, Braun DA, Dittrich S, Pahmeyer C, Schroder P, Teetzen C, Gee H, Daouk G, Pohl M, Kuhn E, Schermer B, Küttner V, Boerries M, Busch H, Schiffer M, Bergmann C, Krüger M, Hildebrandt F, Dengjel J, Benzing T, Huber TB. A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes. Cell Rep [Internet]. 2018;23(8):2495–2508.
Waldron AL, Schroder PA, Bourgon KL, Bolduc JK, Miller JL, Pellegrini AD, Dubois AL, Blaszkiewicz M, Townsend KL, Rieger S. Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity. J Diabetes Complications [Internet]. 2018;32(3):249–257.
Yasuda-Yamahara M, Rogg M, Frimmel J, Trachte P, Helmstaedter M, Schroder P, Schiffer M, Schell C, Huber TB. FERMT2 links cortical actin structures, plasma membrane tension and focal adhesion function to stabilize podocyte morphology. Matrix Biol [Internet]. 2018;68–69:263–279.
Yin VP. In Situ Detection of MicroRNA Expression with RNAscope Probes. Methods Mol Biol [Internet]. 2018;1649:197–208.
Andralojc KM, Campbell AC, Kelly AL, Terrey M, Tanner PC, Gans IM, Senter-Zapata MJ, Khokhar ES, Updike DL. ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans. PLoS Genet [Internet]. 2017;13(2):e1006611.
Duong M, Yu X, Teng B, Schroder P, Haller H, Eschenburg S, Schiffer M. Protein kinase C ϵ stabilizes β-catenin and regulates its subcellular localization in podocytes. J Biol Chem [Internet]. 2017;292(29):12100–12110.
Godwin JW, Debuque R, Salimova E, Rosenthal NA. Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape. NPJ Regen Med [Internet]. 2017;2.
Lisse TS, Rieger S. IKKα regulates human keratinocyte migration through surveillance of the redox environment. J Cell Sci [Internet]. 2017;130(5):975–988.
Müller-Deile J, Dannenberg J, Schroder P, Lin M-H, Miner JH, Chen R, Bräsen J-H, Thum T, Nyström J, Staggs LB, Haller H, Fiedler J, Lorenzen JM, Schiffer M. Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases. Kidney Int [Internet]. 2017;92(4):836–849.
Rochester JD, Tanner PC, Sharp CS, Andralojc KM, Updike DL. PQN-75 is expressed in the pharyngeal gland cells of Caenorhabditiselegans and is dispensable for germline development. Biol Open [Internet]. 2017 Sep 15;6(9):1355–1363.
Rollins JA, Howard AC, Dobbins SK, Washburn EH, Rogers AN. Assessing Health Span in Caenorhabditis elegans: Lessons From Short-Lived Mutants. J Gerontol A Biol Sci Med Sci [Internet]. 2017 Apr 1;72(4):473–480.
Smith AM, Maguire-Nguyen KK, Rando TA, Zasloff MA, Strange KB, Yin VP. The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues. NPJ Regen Med [Internet]. 2017;2:4.
Updike D. swt-3 transcripts are expressed in Z1/Z4 during embryogenesis and in the adult spermatheca. microPublication Biol [Internet]. 2017 Jul 20;2017.
Updike D. acdh-1 transcripts are expressed in the intestine. microPublication Biol [Internet]. 2017 Jul 20;2017.
Zaremba A, Miller DS, Fricker G. Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus). Toxicol Appl Pharmacol. 2017 Nov 1;334:88-99 [/expandsub1]
Bodnar AG, Coffman JA. Maintenance of somatic tissue regeneration with age in short- and long-lived species of sea urchins. Aging Cell [Internet]. 2016;15(4):778–87.
Hartig EI, Zhu S, King BL, Coffman JA. Cortisol-treated zebrafish embryos develop into pro-inflammatory adults with aberrant immune gene regulation. Biol Open [Internet]. 2016 Aug 15;5(8):1134–41.
Howard AC, Rollins J, Snow S, Castor S, Rogers AN. Reducing translation through eIF4G/IFG-1 improves survival under ER stress that depends on heat shock factor HSF-1 in Caenorhabditis elegans. Aging Cell [Internet]. 2016 Dec;15(6):1027–1038.
King BL, Shi LF, Kao P, Clusin WT. Calcium activated K+ channels in the electroreceptor of the skate confirmed by cloning. Details of subunits and splicing. Gene [Internet]. 2016 Mar 1;578(1):63–73.
King BL, Yin VP. A Conserved MicroRNA Regulatory Circuit Is Differentially Controlled during Limb/Appendage Regeneration. PLoS One [Internet]. 2016;11(6):e0157106.
Korstanje R, Deutsch K, Bolanos-Palmieri P, Hanke N, Schroder P, Staggs L, Bräsen JH, Roberts ISD, Sheehan S, Savage H, Haller H, Schiffer M. Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria. J Am Soc Nephrol [Internet]. 2016 Nov;27(11):3271–3277.
Lee EC, Kim H, Ditano J, Manion D, King BL, Strange K. Abnormal Osmotic Avoidance Behavior in C. elegans Is Associated with Increased Hypertonic Stress Resistance and Improved Proteostasis. PLoS One [Internet]. 2016;11(4):e0154156.
Lisse TS, King BL, Rieger S. Comparative transcriptomic profiling of hydrogen peroxide signaling networks in zebrafish and human keratinocytes: Implications toward conservation, migration and wound healing. Sci Rep [Internet]. 2016 Feb 5;6:20328.
Lisse TS, Middleton LJ, Pellegrini AD, Martin PB, Spaulding EL, Lopes O, Brochu EA, Carter E V, Waldron A, Rieger S. Paclitaxel-induced epithelial damage and ectopic MMP-13 expression promotes neurotoxicity in zebrafish. Proc Natl Acad Sci U S A [Internet]. 2016 Apr 12;113(15):E2189-98.
Losick VP, Jun AS, Spradling AC. Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals. PLoS One [Internet]. 2016;11(3):e0151251.
Rizzo F, Coffman JA, Arnone MI. An Elk transcription factor is required for Runx-dependent survival signaling in the sea urchin embryo. Dev Biol [Internet]. 2016;416(1):173–186.
Telles CJ, Decker SE, Motley WW, Peters AW, Mehr AP, Frizzell RA, Forrest JN. Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: implications for cystic fibrosis. Am J Physiol Cell Physiol [Internet]. 2016 Dec 1;311(6):C884–C894.
Teng B, Schroder P, Müller-Deile J, Schenk H, Staggs L, Tossidou I, Dikic I, Haller H, Schiffer M. CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes. Diabetes [Internet]. 2016 Dec;65(12):3667–3679.
Wu C-W, Deonarine A, Przybysz A, Strange K, Choe KP. The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK. PLoS Genet [Internet]. 2016 Oct;12(10):e1006361.
Yamada T, Krzeminski M, Bozoky Z, Forman-Kay JD, Strange K. Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel. Biophys J [Internet]. 2016 Nov 1;111(9):1876–1886.
Yamada T, Strange K. Regulatory Conformational Coupling between CLC Anion Channel Membrane and Cytoplasmic Domains. Biophys J [Internet]. 2016 Nov 1;111(9):1887–1896.
Yamada T, Wondergem R, Morrison R, Yin VP, Strange K. Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish. Physiol Rep [Internet]. 2016;4(19).
Zhao H, Rieger S, Abe K, Hewison M, Lisse TS. DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization. Int J Mol Sci [Internet]. 2016 Nov 26;17(12).